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Interactions for Magnesium

Possible Interactions with Magnesium

Overview

Penicillamine, a medication used for the treatment of Wilson's disease and rheumatoid arthritis, can inactivate magnesium, particularly when high doses are used over a long period of time.

Aminoglycoside antibiotics (such as gentamicin and tobramycin), thiazide diuretics (such as hydrochlorothiazide), and loop diuretics (such as furosemide and bumetanide) may lower magnesium levels. Amphotericin B, corticosteroids, and antacids can also reduce blood levels of magnesium.

Insulin and digoxin can lower magnesium levels. Although adequate levels of magnesium can enhance the effectiveness of both medications, consult your health care provider before taking magnesium supplements.

Magnesium may increase the likelihood of negative side effects (such as dizziness, nausea, and leg swelling) from calcium channel blockers, particularly nifedipine, that are used to control blood pressure. Pregnancy increases the likelihood of this interaction.

Drug Interactions

Related Information
Table of Contents
Magnesium
Uses of this Supplement
  Anxiety
  Asthma
  Depression
  Diabetes Mellitus
  Glaucoma
  Headache, Migraine
  Heart Attack
  High Blood Pressure
  High Cholesterol
  Kidney Stones
  Menstrual Pain
  Preeclampsia
  Premenstrual Syndrome (PMS)
  Stroke
  Water Retention
Supplements with Similar Uses
  View List by Use
Drugs that Interact
  Summary
    Calcium-channel blockers
    Corticosteriod medications
    Digoxin
    Insulin
    Loop diuretics
    Thiazide diuretics
Drugs that Deplete this Nutrient
  View List
Supplements with Similar Warnings
  View List by Warning
Learn More About
  Nutrition

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