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  Magnesium

Magnesium

The mineral magnesium is important for your heart, muscles, and kidneys. It is part of what makes up your teeth and bones. Most important, it activates enzymes, giving you energy and helping your body work properly. It can help reduce stress, depression, and insomnia. Vitamin B6 helps you get the magnesium you need and works with magnesium in many ways.

Magnesium is available in many foods. However, most people in the United States probably do not get as much magnesium as they should from their diet. Nutrition tables can give you only a rough idea of how much magnesium you are getting. Scientists have found that different ways of determining the amount of magnesium in foods produce different results. Also, many foods have not been thoroughly analyzed.

Certain medical conditions can upset your body's magnesium balance. For example, intestinal flu with vomiting or diarrhea can cause temporary deficiencies. Long-term deficiencies can be caused by stomach and bowel diseases, diabetes, pancreatitis, kidney malfunction, and diuretics. Talk with your health care provider about your magnesium needs if you have any of these conditions.

Uses

Getting enough magnesium can help you in the following ways:

  • Prevent hardening of the arteries (arteriosclerosis)
  • Prevent strokes and heart attacks
  • Reduce your blood pressure
  • Lower your cholesterol and triglyceride levels
  • Correct heart arrhythmias
  • Stop acute asthma attacks
  • Decrease your insulin needs if you have diabetes
  • Prevent kidney stones
  • Treat Crohn's disease
  • Treat noise-induced hearing loss
  • Improve your vision if you have glaucoma
  • Reduce cramps, irritability, fatigue, depression, and water retention associated with menstruation
  • Prevent serious complications of pregnancy, such as preeclampsia and eclampsia
  • Restore your normal energy level
  • Improve your sleep
  • Reduce anxiety and depression
  • Reduce the effects of stress

Dietary Sources

The richest sources of magnesium are tofu, nuts (Brazil nuts, almonds, cashews, black walnuts, pine nuts), pumpkin and squash seeds, peanuts, green leafy vegetables, legumes, wheat bran, whole grains, soybean flour, blackstrap molasses.

Other good sources are whole wheat flour, oat flour, beet greens, spinach, shredded wheat, bran cereals, oatmeal, bananas, baked potatoes (with the skin), pistachio nuts.

You can also get magnesium from many herbs, spices, and seaweeds (for example, agar seaweed, coriander, dill weed, celery seed, sage, dried mustard, basil, cocoa powder, fennel seed, savory, cumin seed, tarragon, marjoram, and poppy seed).

Other Forms

Magnesium is available in many forms. The best supplements are labeled "soluble," which means it's easier for your body to absorb the magnesium it needs. These come in gelatin capsules. Recommended types include magnesium citrate, magnesium gluconate, and magnesium lactate.

Other familiar sources of magnesium are milk of magnesia (magnesium hydroxide), often used as a laxative or antacid, Epsom salts (magnesium sulfate) used as a laxative or tonic, or added to a bath. Some magnesium can be absorbed through the skin.

How to Take It

You should take small doses of magnesium throughout the day, with a full glass of water with each dose to avoid diarrhea. These are the recommended daily amounts:

  • Adult men ages 19 to 30: 400 mg; after age 30: 420 mg
  • Adult women ages 19 to 30: 310 mg; after age 30: 320 mg
  • Boys ages 14 to 18: 410 mg
  • Girls ages 14 to 18: 360 mg
  • Children ages 9 to 13: 240 mg; children ages 4 to 8: 130 mg; children ages 1 to 3: 80 mg

Precautions

Do not take magnesium supplements if you have severe heart disease or kidney disease without talking with your health care provider.

Overuse of milk of magnesia (as a laxative or antacid) or Epsom salts (as a laxative or tonic) can cause you to ingest too much magnesium, especially if you have kidney problems. Too much magnesium can cause serious health problems and even death.

Possible Interactions

Penicillamine, a medication used for the treatment of Wilson's disease and rheumatoid arthritis, can inactivate magnesium, particularly when high doses are used over a long period of time.

Aminoglycoside antibiotics (such as gentamicin and tobramycin), thiazide diuretics (such as hydrochlorothiazide), and loop diuretics (such as furosemide and bumetanide) may lower magnesium levels. Amphotericin B, corticosteroids, and antacids can also reduce blood levels of magnesium.

Insulin and digoxin can lower magnesium levels. Although adequate levels of magnesium can enhance the effectiveness of both medications, consult your health care provider before taking magnesium supplements.

Magnesium may increase the likelihood of negative side effects (such as dizziness, nausea, and leg swelling) from calcium channel blockers, particularly nifedipine, that are used to control blood pressure. Pregnancy increases the likelihood of this interaction.

Supporting Research

Britton J, Pavord I, Richards K, Wisniewski A, Knox A, Lewis S. Dietary magnesium, lung function, wheezing, and airway hyperactivity in a random adult population sample. Lancet. 1994; 344:357–362.

Crippa G, Sverzellati E, Girogi Pierfranceschi M, Carrara GC. Magnesium and cardiovascular drugs: interactions and therapeutic role. Ann Ital Med Int. 1999;14(1):40-45.

Davis WB, Wells SR, Kuller JA, Thorp JM Jr. Analysis of the risks associated with calcium channel blockade: implications for the obstetrician-gynecologist. Obstet Gynecol Surv. 1997; 52(3):198-201.

De Valk HW. Magnesium in diabetes mellitus. Neth J Med. 1999;54(4):139-146.

Ensminger AH, Ensminger ME, Konlande JE, Robson JRK. Foods and Nutrition Encyclopedia. 2nd ed. Baton Rouge, Fla: CRC Press Inc; 1994;2:1338–1341.

Garrison Jr RH, Somer E. The Nutrition Desk Reference. 3rd ed. New Canaan, Conn: Keats Publishing Inc; 1995:158–165.

Hardman JG, Gilman AG, Limbird LE, eds. Goodman and Gilman's Pharmacological Basis of Therapeutics. 9th ed. New York, NY: McGraw-Hill; 1996:839–874.

Heinerman J. Heinerman's Encyclopedia of Nature's Vitamins and Minerals. Paramus, NJ: Prentice Hall Inc; 1998:296–302.

Matsumura M, Nakashima A, Tofuku Y. Electrolyte disorders following massive insulin overdose in a patient with type 2 diabetes. Intern Med. 2000;39(1):55-57.

Mersebach H, Rasmussen AK, Kirkegaard L, Feldt-Rasmussen U. Intestinal absorption of levothyroxine by antacids and laxatives: case stories and in vitro experiments. Pharmacol Toxicol. 1999;84(3):107-109.

Murray MT. Encyclopedia of Nutritional Supplements. Rocklin, Calif: Prima Publishing; 1996:159–175.

Physicians’ Desk Reference. 54th ed. Montvale, NJ: Medical Economics Co., Inc.; 2000:1215-1218.

Posaci C, Erten O, Uren A, Acar B. Plasma copper, zinc and magnesium levels in patients with premenstrual tensions syndrome. Obstetricia et Gynecologica Scandinavica. 1994; 73:452–455.

Romano TJ. Magnesium deficiency in systemic lupus erythematosus. J Nutr Environ Med. 1997;7:107–111.

Romano TJ, Stiller JW. Magnesium deficiency in fibromyalgia syndrome. J Nutr Med. 1994;4:165–167.

Sacks FM, Willett WC, Smith A, Brown LB, Rosner B, Moore TJ. Effect on blood pressure of potassium, calcium, and magnesium in women with low habitual intake. Hypertension. 1998;31:131–138.

Seelig MS. Auto-immune complications of D-penicillamine – a possible result of zinc and magnesium depletion and of pyridoxine inactivation. J Am Coll Nutr. 1982;1(2):207-214.

Shils ME, Olson JA, Shike M, Ross AC. Modern Nutrition in Health and Disease. 9th ed. Baltimore, Md: Williams & Wilkins; 1999:169–192, A127–A128.

Werbach MR. Nutritional Influences on Illness. 2nd ed. Tarzana, Calif: Third Line Press; 1993:655–680.


Copyright © 2000 Integrative Medicine Communications

The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. No claims or endorsements are made for any drugs or compounds currently marketed or in investigative use. This material is not intended as a guide to self-medication. The reader is advised to discuss the information provided here with a doctor, pharmacist, nurse, or other authorized healthcare practitioner and to check product information (including package inserts) regarding dosage, precautions, warnings, interactions, and contraindications before administering any drug, herb, or supplement discussed herein.

           
                                                    

                         

                                

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