Ginseng may increase the effects of caffeine or other medications that
stimulate the central nervous system, possibly making you feel nervous or
causing sweating, insomnia, or irregular heartbeat. Therefore it is safest not
to use ginseng with such medications.
Ginseng may increase the effects of antidepressant medications (medicines to
treat depression), specifically, the MAO inhibitor phenelzine. It may also
interact with corticosteroid medications as well as medications used to regulate
blood pressure and to control blood sugar levels (diabetes). If you are using
any of these medications, do not take ginseng without first consulting your
health care provider.