Chronic internal use of aloe could cause potassium deficiency. Low potassium
levels can interfere with certain heart medications, like digoxin or other
antiarrhythmic medications used to correct irregular heartbeat. The potential
for potassium deficiency is greater if you use aloe with licorice,
corticosteroid medications, and most diuretics (except potassium-sparing
diuretics that do not deplete potassium levels). It is best to avoid taking aloe
with any of these medications.