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  Aloe

Aloe

Aloe vera has a long history of use as a medicinal plant, with written records of its use going back to 1750 BC. Today it is grown in most subtropical and tropical locations, including the Caribbean, southern United States, Latin America, and the Middle East. Many people also grow a small potted version indoors for use in healing minor burns and cuts.

Plant Description

Aloe vera is a perennial plant with yellow flowers. Its tough, fleshy, spearlike leaves can grow up to 20 inches long, and the whole plant up to 4 feet high. Only the leaves are used for medicine, but different parts of the leaves are used for different purposes. The clear, thick gel that is most commonly associated with aloe vera comes from the inner part of the leaf. Between this gel and the outer skin of the leaf are some special cells that contain a bitter yellow juice. When this juice is dried, it forms aloe latex.

What's It Made Of?

Aloe gel contains glycoproteins, which stop pain and inflammation and speed the healing process, and polysaccharides, which stimulate skin growth and repair. The anthraquinones in aloe latex work as powerful laxatives, and in smaller amounts, these chemicals can help stop kidney stone formation.

Aloe gel can be used to heal both internal and external wounds. It greatly speeds the healing of many skin injuries, including ulcerations, burns, and frostbite. Aloe latex is a powerful laxative, but because it can cause painful cramping, it is not used frequently. In smaller doses, aloe latex can help prevent kidney stones or reduce their size. It is also useful as a stool softener, particularly in people who have painful hemorrhoids.

Aloe juice is a liquid form of aloe gel that you can take internally. Because it has antibacterial properties, aloe juice can be used to treat bacterial infections in the gastro-intestinal tract. It is also effective for healing peptic ulcers because it reduces the stomach acids that aggravate ulcers.

Recent studies have shown that acetylated mannose, an antiviral component of aloe, has important HIV-fighting properties. Acetylated mannose attacks the virus itself, but more important, it greatly enhances the action of AZT, a powerful drug used to treat HIV infection. If taken in conjunction with aloe, the amount of AZT taken for HIV could be reduced by 90 percent, which would greatly reduce the expense and side effects associated with AZT.

Available Forms

Aloe gel is best fresh from an aloe plant, but it is also available commercially in a stabilized gel form. Aloe latex is available in a powdered form or in 500-mg capsules for use as a laxative. Aloe juice is a liquid form of the gel.

How to Take It

Aloe gel is best when taken fresh from the plant. Many people keep an aloe plant in their kitchen to treat minor burns or cuts. It can also be effective for treating hives and poison ivy. To use the gel, slit a leaf lengthwise and remove the gel inside. Apply liberally to affected area.

Aloe latex has been used traditionally as a laxative, but it is used infrequently in the US. Because it can produce painful cramping, other gentler herbal laxatives such as cascara and senna are recommended first.

For kidney stones and as a stool softener, take 0.05 to 0.2 grams of dry aloe extract (latex).

For HIV, take 800 to 1600 mg of acetylated mannose per day. This is equivalent to .5 to 1 liter of aloe vera juice, although amounts of acetylated mannose may vary in different products.

Precautions

Aloe gel is safe for external use, unless it causes a rare allergic reaction. Discontinue use if it irritates the skin. Aloe gel is not useful for treatment of deep wounds. Aloe latex may cause severe intestinal cramps or diarrhea. Pregnant or nursing women should not take aloe latex because it may cause uterine contractions and trigger miscarriage. Aloe latex is not recommended for gastrointestinal illness, intestinal obstruction, appendicitis, or stomach pain of unknown cause. It may aggravate ulcers, hemorrhoids, diverticulosis, diverticulitis, colitis, or irritable bowel syndrome. If it's taken over a long period of time, aloe latex can cause dependence or disturb the electrolyte balance. It may also cause urine to turn a harmless red color. Children under 12 should not use aloe latex.

Possible Interactions

Chronic internal use of aloe could cause potassium deficiency. Low potassium levels can interfere with certain heart medications, like digoxin or other antiarrhythmic medications used to correct irregular heartbeat. The potential for potassium deficiency is greater if you use aloe with licorice, corticosteroid medications, and most diuretics (except potassium-sparing diuretics that do not deplete potassium levels). It is best to avoid taking aloe with any of these medications.

Supporting Research

Blitz JJ, et al. Aloe vera gel in peptic ulcer therapy: preliminary report. J Am Osteopath Assoc. 1963;62:731–735.

Blumenthal M, ed. The Complete German Commission E Monographs. Boston, Mass: Integrative Medicine Communications. 1998.

Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, Ore: Eclectic Medical; 1998:28-30.

Brinker F. The Toxicology of Botanical Medicines. Rev 2nd ed. Sandy, Ore: Eclectic Medical; 1996.

Castleman M. The Healing Herbs. New York, NY: Bantam Books. 1991.

Chauhan O, Godhwani JL, Khanna NK, et al. Anti-inflammatory activity of Muktashukti bhasma. Indian J Exp Biol. 1998;36(10):985–989.

Danhof I. Potential benefits from orally-injested internal aloe vera gel. International Aloe Science Council Tenth Annual Aloe Scientific Semina; 1991; Irving, Texas.

De Smet PAGM, et al, eds. Adverse Effects of Herb Drugs 2. Berlin, Germany: Springer-Verlag; 1993.

Desai KN, Wei H, Lamartiniere CA. The preventive and therapeutic potential of the squalene-containing compound, Roidex, on tumor promotion and regression. Cancer Lett. 1996; 101(1):93-96.

Duke J. The Green Pharmacy. Emmaus, Penn: Rodale Press. 1997.

Fahim MS, Wang M. Zinc acetate and lyophilized Aloe barbadensis as vaginal contraceptive. Contraception. 1996;53:231–236.

Fulton JE Jr. The stimulation of postdermabrasion wound healing with stabilized aloe vera gel-polyethylene oxide dressing. J Dermatol Surg Onco. 1990;16:460.

Grindlay D, Reynolds T. The aloe vera phenomenon: a review of the properties and modern uses of the leaf parenchyma gel. J Ethnopharmacol. 1986;16:117–151.

Gruenwald J, Brendler T, Jaenicke C et al, eds. PDR for Herbal Medicines. Montvale, NJ: Medical Economics Company. 1998.

Heggers J, et al. Beneficial effects of aloe in wound healing. Phytother Res. 1993;7:S48–S52.

Murray M, Pizzorno J. Encyclopedia of Natural Medicine. Rocklin, Calif: Prima Publishing. 1991.

Murray M. Healing Power of Herbs. Rocklin, Calif: Prima Publishing. 1995.

Newall C, et al. Herbal Medicines. London, England: Pharmaceutical Press. 1996.

Paszkiewicz-Gadek A, Chlabicz J, Galasinski W. The influence of selected potential oncostatics of plant origin on the protein biosynthesis in vitro. Pol J Pharmacol. 1988;40(2):183–190.

Plemmons JM, et al. Evaluation of acemannan in the treatment of aphthous stomatitis. Wounds.1994;6.

Ryndina AM, Lin'kov VI, Dadiomova MA, et al. Experience using antihypoxic drugs in the treatment of acute neurosensory hearing loss in children with meningitis [in Russian]. Vestn Otorinolaringol. 1989;Mar–Apr(2):14–17.

Saoo K, et al. Antiviral activity of aloe extracts against cytomegalovirus. Phytother Res. 1996;10:348–350.

Schmidt JM, Greenspoon JS. Aloe vera dermal wound gel is associated with a delay in wound healing. Ostet Gynecol. 1991;78(1).

Shida, T. et al. 1985. Effect of aloe extract on peripheral phagocytosis in adult bronchial asthma. Planta Med 51.

Schmidt JM, Greenspoon JS. Aloe vera dermal wound gel is associated with a delay in wound healing. Ostet Gynecol. 1991;78(1).

Syed TA, et al. Management of psoriasis with aloe vera extract in a hydrophilic cream: a placebo-controlled, double-blind study. Trop Med Int Health. 1996;1:505–509.

Tyler V. The Honest Herbal. New York, NY: Pharmaceutical Products Press. 1993.

Vazquez B, et al. Anti-inflammatory activity of extracts from aloe vera gel. JEthnopharmacol. 1996;55:69–75.

Wichtl M, ed. Herbal Drugs and Phytopharmaceuticals. 2nd ed. Boca Raton, Fla: CRC Press; 1994.


Copyright © 2000 Integrative Medicine Communications

The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. No claims or endorsements are made for any drugs or compounds currently marketed or in investigative use. This material is not intended as a guide to self-medication. The reader is advised to discuss the information provided here with a doctor, pharmacist, nurse, or other authorized healthcare practitioner and to check product information (including package inserts) regarding dosage, precautions, warnings, interactions, and contraindications before administering any drug, herb, or supplement discussed herein.

           
                                                    

                         

                                

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