St. John's wort may interact with antidepressant medication that are used to
treat depression or other mood disorders. Therefore, do not take this herb with
any such medications.
You should not take St. John's wort if you are taking the heart medication
digoxin because of the potentially dangerous interaction between this herb and
this medication.
Using St. John's wort with antiviral agents like indinavir and other protease
inhibitors is not recommended. There is the possibility of an interaction
between this herb and these medications that could undermine the effectiveness
of the antiviral medications.
You should not take this herb with immunosuppressive medications like
cyclosporin because it may reduce the effectiveness of these medications.
