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Lisinopril and Hydrochlorothiazide
Lisinopril and Hydrochlorothiazide
Pronunciation
(lyse IN oh pril & hye droe klor oh THYE a zide)
Brand Names
Prinzide®; Zestoretic®
Therapeutic Categories
Angiotensin-Converting Enzyme (ACE) Inhibitor Combination; Antihypertensive
Agent, Combination
What is this medicine used for?
- This medicine is used to treat high blood pressure.
How does it work?
- Lisinopril lowers blood pressure by decreasing production of a strong
chemical in the body that increases blood pressure.
- Hydrochlorothiazide (HCTZ) lowers blood pressure and can act to get rid of
extra salt and water in the body. It works on the kidneys.
How is it best taken?
- Take with or without food. Take with food if this medicine causes an upset
stomach.
- Take at a similar time every day. Taking early in the day may be better to
prevent getting up at night to use the bathroom.
- Follow diet plan (low salt) as recommended by healthcare provider.
What do I do if I miss a dose?
- Take a missed dose as soon as possible.
- If it is almost time for the next dose, skip the missed one. Return to your
regularly scheduled one.
- Do not take a double dose or extra doses.
What are the precautions when taking this
medicine?
- Wear disease medical alert identification for high blood pressure.
- Limit alcohol intake (includes wine, beer, and liquor) if you are taking
this medicine for high blood pressure. Can increase blood pressure.
- If you are diabetic watch blood sugar. Medicine may decrease blood sugar.
Diabetic medicines may need adjustment.
- Not for use in kidney disease. Talk with healthcare provider.
- Watch for gout attacks. If you have sudden pain in a single joint, like the
toe, talk with healthcare provider.
- You can get sunburned more easily. Avoid lots of sun. Use sunscreen; wear
protective clothing and eyewear.
- Do not use over-the-counter products that increase blood pressure. These
include cough or cold remedies, diet pills, stimulants, ibuprofen or like
products, and certain herbs or supplements. Talk with healthcare provider.
- Tell healthcare provider if you are allergic to any medicine. Make sure to
tell about the allergy and how it affected you. This includes telling about
rash; hives; itching; shortness of breath; wheezing; cough; swelling of face,
lips, tongue, throat; or any other symptoms involved.
- Do not use in pregnancy and do not get pregnant. Use birth control that you
can trust while taking this medicine.
- Tell healthcare provider if you are breast-feeding.
What are the common side effects of this
medicine?
- Dizziness is common. Rise slowly over several minutes from sitting or lying
position. Be careful climbing stairs.
- Lightheaded. Avoid driving, doing other tasks or hobbies that require you
to be alert until you see how this medicine affects you.
- Abnormal taste (metallic, salty, or none). This is usually reversible.
- Dry cough.
What should I monitor?
- Check blood pressure regularly.
- Follow diet plan and exercise program as recommended by healthcare
provider.
- Check blood work (potassium). Talk with healthcare provider.
Reasons to call healthcare provider
immediately
- Signs of a life-threatening reaction. These include wheezing; tightness in
the chest; fever; itching; bad cough; blue skin color; fits; swelling of face,
lips, tongue, or throat.
- Passing out, fainting, dizziness, or lightheadedness.
- Any rash.
How should I store this medicine?
- Store in a tight container at room temperature.
General statements
- Do not share your medicine with others and do not take anyone else's
medicine.
- Keep all medicine out of the reach of children and pets.
- Keep a list of all your medicines (prescription, herbal/supplements,
vitamins, over-the-counter) with you. Give this list to healthcare provider
(doctor, nurse, pharmacist, physician assistant).
- Talk with healthcare provider before starting any new medicine, including
over-the-counter or natural products (herbs, vitamins).
Copyright © 1978-2000 Lexi-Comp Inc. All Rights Reserved
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