Vanadium
Vanadium is an essential trace mineral. It is
present in varying amounts in the soil and in many foods. It can also be inhaled
from the air as a result of burning petroleum or petroleum products. At the end
of the last century, vanadium was thought to be a cure for various diseases, but
it turned out to be toxic at the high doses prescribed. Vanadium is necessary
for bone and tooth development. Too little vanadium may result in high
cholesterol and triglyceride levels, poor blood sugar control (for example,
diabetes or hypoglycemia), and cardiovascular and kidney disease. However, the
effects of vanadium deficiency in humans have not been studied.
Uses
- Vanadium improves blood sugar control in experimental animals
with type 1 and type 2 diabetes mellitus; however, no human studies have been
conducted to support these findings.
- High doses of vanadium improve the strength of bones and teeth
in experimental animals.
- Studies have not been able to determine definitively any
performance-enhancing effects of vanadium (for example, in body
building).
- Vanadium may reduce cholesterol in experimental
animals.
- Heart disease rates are low in areas of the world (for example,
South America) where soils contain high levels of vanadium. No cause and effect
relationship has been demonstrated, however.
Dietary Sources
The best sources of vanadium are sunflower, safflower, corn, and olive oils,
as well as buckwheat, parsley, oats, rice, green beans, carrots, cabbage,
pepper, and dill. It is important to note, however, that only about 5 percent of
vanadium is absorbed by the body; most of it is eliminated in the feces.
Vanadium supplementation is rarely, if ever, necessary. Eating any of the above
foods, particularly vegetable oils, will provide a sufficient amount of
vanadium. Some experts do not recommend taking vanadium supplements until more
is known about how this mineral affects the human body.
Other Forms
Vanadium exists in several forms, including vanadyl and vanadate. Vanadyl
sulfate is most commonly found in nutritional supplements. Because of its
toxicity, some experts believe that vanadium should be considered a drug and not
a nutritional supplement.
How to Take It
Typical over-the-counter doses of vanadium are 30 to 60 mg per day in pill
form.
Precautions
- Animal studies have not proven the efficacy or safety of
vanadium in humans.
- Extremely high doses of inhaled vanadium (for example, in
workers who clean petroleum storage tanks) irritate the lungs and turn the
tongue green, but neither symptom causes any long-term or serious
problems.
- High levels of vanadium may cause manic-depression.
- High levels of vanadium may contribute to some bone and kidney
diseases.
Possible Interactions
No harmful drug interactions have been reported.
Supporting Research
Balch JF, Balch PA. Prescription for Nutritional Healing.
Garden City Park, NY: Avery Publishing; 1997:29.
Bender DA, Bender AE. Nutrition: A Reference Handbook.
New York, NY: Oxford University Press; 1997:424.
Murray MT. Encyclopedia of Nutritional Supplements. Rocklin,
Calif: Prima Publishing; 1996:232–234.
Murray MT, Pizzorno JE. Enclyclopedia of Natural Medicine. 2nd
ed. Rocklin, Calif: Prima Publishing; 1998:283–284.
Shealy CN. The Illustrated Encyclopedia of Healing Remedies.
Boston, Mass: Element Books; 1998:268.
Role of vanadium as a mimic of insulin. Nutri Res Newslett.
1998;17:11.
Werbach MR. Nutritional Influences on Illness. New Canaan,
Conn: Keats Publishing; 1987:87–88, 159.
Yale J-F, Lachance D, Bevan AP. Hypoglycemic effects
of peroxovanadium compounds in Sprague-Dawley and diabetic BB rats. Diabetes.
1995;44:1274–1276.
Copyright © 2000 Integrative Medicine
Communications
The publisher does not accept any responsibility for the
accuracy of the information or the consequences arising from the application,
use, or misuse of any of the information contained herein, including any injury
and/or damage to any person or property as a matter of product liability,
negligence, or otherwise. No warranty, expressed or implied, is made in regard
to the contents of this material. No claims or endorsements are made for any
drugs or compounds currently marketed or in investigative use. This material is
not intended as a guide to self-medication. The reader is advised to discuss the
information provided here with a doctor, pharmacist, nurse, or other authorized
healthcare practitioner and to check product information (including package
inserts) regarding dosage, precautions, warnings, interactions, and
contraindications before administering any drug, herb, or supplement discussed
herein.