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  Flaxseed Oil

Flaxseed Oil

Flaxseed oil is rich in a type of fat called alpha-linolenic acid (ALA), an essential fatty acid used as a source of energy by the body. It also serves as the parent substance to compounds that regulate blood pressure, blood clotting, heart rate, blood vessel dilation, the immune response, and the breakdown of fats. Essential fatty acids are also used to make brain and nerve tissue.

ALA is a member of a family of fats called omega-3 fatty acids. Flaxseed oil and fish oils are the richest sources of omega-3 fatty acids. Canola oil and soybean oils also contain some omega-3 fatty acids. Corn, safflower, cottonseed, sesame, and sunflower oils are rich in fats called omega-6 fatty acids. These two families of fats have very important, but different, roles in the body. It is important to have a balance of omega-6 and omega-3 fatty acids in the diet. Excessive intake of either type of fat can cause health problems.

American diets are typically high in omega-6 fatty acids and low in omega-3 fatty acids. Taking in more omega-6 than omega-3 fatty acids through your diet may cause your body to produce substances that cause inflammation and negatively affect your body's response to disease. These imbalances may make you more susceptible to heart disease, inflammatory conditions such as arthritis and psoriasis, and infections, and can lower your immunity. You may gain significant health benefits by increasing the level of omega-3 fatty acids in your diet. This is especially true if you take in large amounts of omega-6 fatty acids.

Uses

Here is a partial list of illnesses that may be prevented or treated with flaxseed oil.

  • Skin disorders. Flaxseed oil may reduce the itching, swelling, and redness associated with certain skin disorders such as psoriasis.
  • Hypertension. One tablespoon of flaxseed oil per day appears to be effective in lowering blood pressure.
  • Heart disease. ALA may reduce the risk of heart disease by improving the function and integrity of arteries that carry blood throughout the body and to the brain. High doses of ALA may reduce blood cholesterol and triglyceride levels.
  • Diabetes. Flaxseed oil may help reduce cholesterol and triglyceride levels in some people with diabetes. However, some people with type 2 diabetes cannot properly metabolize ALA, so flaxseed oil may be of no benefit to them.
  • Autoimmune disorders. These disorders, such as rheumatoid arthritis and ulcerative colitis, cause immune cells to attack healthy tissue in the body. Flaxseed oil is converted to a substance in the body that can inhibit this autoimmune reaction.

Dietary Sources

Flaxseed oil is found in flaxseed or flaxseed meal. Flaxseed oil is the richest source of omega-3 fatty acids, containing approximately 55 to 65 percent of the essential fatty acid ALA. It also contains the natural antioxidants beta-carotene (vitamin A) and carotenoids.

Other Forms

Flaxseed oil is available in liquid and softgel capsule form, and, like any oil, should be refrigerated to prevent it from becoming rancid. Flaxseed oil requires special packaging because it is easily destroyed by heat, light, and oxygen. The highest quality flaxseed products are manufactured using fresh pressed seeds, are bottled in dark or opaque containers, and processed at low temperatures in the absence of light, extreme heat, or oxygen.

How to Take It

Because flaxseed oil is easily damaged by heat and light, it must be added to foods after they have been cooked. Use flaxseed oil as a salad dressing, in dips, sprayed over popcorn, or add it to hot or cold cereal.

For the prevention and treatment of disease adults should take 1 to 3 tsp. per day.

As with all dietary supplements, check with a health care provider before giving flaxseed oil to a child.

Precautions

Flaxseed oil will add additional calories and fat to your diet unless you reduce your intake of other fats.

Possible Interactions

Flaxseed may slow down the absorption of oral medications or other nutrients if taken at the same time. Talk to your health care provider before taking flaxseed if you regularly take any prescription or over-the-counter medications.

Supporting Research

Allman-Farinelli MA, Hall D, Kingham K, Pang D, Petocz P, Favaloro EJ. Comparison of the effects of two low fat diets with different alpha-linolenic acid ratios on coagulation and fibrinolysis. Atherosclerosis. 1999;142:159–168.

Bierenbuam ML, Reichstein R, Watkins TR. Reducing atherogenic risk in hyperlipemic humans with flaxseed supplementation: a preliminary report. J Am Coll Nutr. 1993;12:501–504.

Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, Ore: Eclectic Medical; 1998:71-72.

Clark WF, Parbtani A, Hugg MW, et al. Flaxseed: a potential treatment of lupus nephritis. Kidney Int. 1995;48:475–480.

Cunnane SC, Ganguli S, Menard C, et al. High alpha-linolenic acid flaxseed (Linum usitatissimum): some nutritional properties in humans. Br J Nutr. 1993;69:443–453.

Cunnane SC, Hamadeh MJ, Liede AC, Thompson LU, Wolever TM, Jenkins DJ. Nutritional attributes of traditional flaxseed in healthy-young adults. Am J Clin Nutr. 1995;61:62–68.

Das UN, Madhavi N, Sravan KG, Padma M, Sangeetha P. Can tumor cell drug resistance be reversed by essential fatty acids and their metabolites? Prostaglandins Leukot Essent Fatty Acids. 1998;58:39–54.

De Smet PAGM, et al, eds. Adverse Effects of Herb Drugs 2. Berlin, Germany: Springer-Verlag, 1993.

Denis L, Morton MS, Griffiths K. Diet and its preventive role in prostatic disease. Eur Urol. 1999;35(5–6):377–387.

Dox IG, Melloni BJ, Eisner GM. The HarperCollins Illustrated Medical Dictionary. New York, NY: HarperCollins Publishers; 1993.

Gerster H. Can adults adequately convert alpha-linolenic acid (18:3n-3) to eicosapentaenoic acid (20:5n-3) and docosahexaenoic acid (22:6n-3)? Int J Vitam Nutr Res. 1998;68:159–173.

Haggans CJ, Hutchins AM, Olson BA, et al. Effect of flaxseed consumption on urinary estrogen metabolites in postmenopausal women. Nutr Cancer. 1999;33(2):188–195.

Harris WS. N-3 fatty acids and serum lipoproteins: human studies. Am J Clin Nutr. May 1997;65(5 suppl):1645S–1654S.

Heller A, Koch T, Schmeck J, Van Ackern K. Lipid mediators in inflammatory disorders. Drugs. 1998;55:487–496.

Ingram AJ, Parbtani A, Clark WF, Spanner E, Huff MW, Philbrick DJ, Holub BJ. Effects of flax oil diets in a rat-5/6 renal ablation model. Am J Kidney Dis. 1995;25:320–329.

Kaminskas A, Levaciov, Lupinovic V, Kuchinskene Z. The effect of linseed oil on the fatty acid composition of blood plasma low- and very low-density lipoproteins and cholesterol in diabetics [in Russian]. Vopr Pitan. 1992;5–6:13–14.

Leece EA, Allman MA. The relationships between dietary alpha-linolenic: linoleic acid and rat platelet eicosapentaenoic and arachidonic acids. Br J Nutr. 1996;76:447–452.

Mantzioris E, James MJ, Gibson RA, Cleland LG. Differences exist in the relationships between dietary linoleic and alph-linolenic acids and their respective long-chain metabolites. Am J Clin Nutr. 1995;61:320–324.

Mayser P, Mrowietz U, Arenberger P, et al. Omega-3 fatty acid-based lipid infusion in patients with chronic plaque psoriasis: results of a double-blind, randomized, placebo-controlled, multicenter trial. J Am Acad Dermatol. 1998;38:539–547

McGuffin M, Hobbs C, Upton R, et al, eds. Botanical Safety Handbook. Boca Raton, Fla: CRC Press; 1997.

Murray MT, Pizzorno JE. Encyclopedia of Natural Medicine. 2nd ed. Rocklin, Calif: Prima Publishing; 1998.

Nestel PJ, et al. Arterial compliance in obese subjects is improved with dietary plant n-3 fatty acid from flaxseed oil despite increased LDL oxidizability. Arterioscler Thromb Vasc Biol. 1997;17:1163–1170.

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Orten JM, Neuhaus OW, eds. Human Biochemistry. 10th ed. St. Louis, Mo: The C.V. Mosby Company; 1982.

Prasad K. Dietary flaxseed in prevention of hypercholesterolemic atherosclerosis. Atherosclerosis. 1997;132:69–76.

Prasad K. Dietary flaxseed in prevention of hypercholesterolemic atherosclerosis. Atherosclerosis. 1997;132(1):69–76.

Rozanova IA, Pogozheva AV, Miagkova MA. Effect of antiatherosclerotic diet with polyunsaturated fatty acids omega-3 from linseed oil on dynamics of natural antibodies to bradykinin and angiotensin II in blood serum of patients with cardiovascular diseases [in Russia]. Savitskaia IuA Vopr Pitan. 1998;2:32–34.

Shils ME, Olson JA, Shike M, eds. Modern Nutrition in Health and Disease. 8th ed. Media, Pa: Williams and Wilkins Co; 1994:1.

Schmidt MA. Smart Fats: How Dietary Fats and Oils Affect Mental, Physical and Emotional Intelligence. Berkeley, Calif: Frog, Ltd; 1997.

Talom RT, Judd SA, McIntosh DD, et al. High flaxseed (linseed) diet restores endothelial function in the mesenteric arterial bed of spontaneously hypertensive rats. Life Sci. 1999;16:1415–1425.

Valsta LM, Salminen I, Aro A, Mutanen M. Alpha-linolenic acid in rapeseed oil partly compensates for the effect of fish restriction on plasma long chain n-3 fatty acids. Eur J Clin Nutr. 1996;50:229–235.

Wichtl M, ed. Herbal Drugs and Phytopharmaceuticals. Boca Raton, Fla: CRC Press; 1994.


Copyright © 2000 Integrative Medicine Communications

The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. No claims or endorsements are made for any drugs or compounds currently marketed or in investigative use. This material is not intended as a guide to self-medication. The reader is advised to discuss the information provided here with a doctor, pharmacist, nurse, or other authorized healthcare practitioner and to check product information (including package inserts) regarding dosage, precautions, warnings, interactions, and contraindications before administering any drug, herb, or supplement discussed herein.

           
                                                    

                         

                                

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