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  Cat's Claw

Cat's Claw

Tribal people in the regions where cat's claw grows have used medicines prepared from the root bark for at least 2,000 years. They've used it to treat so many illnesses that it sounds like an amazing superdrug. For example, sexually transmitted diseases, arthritis, ulcer, and cancer are all reported to be cured by cat's claw.

After these claims got the attention of scientists in Europe, tests were able to show that ingredients in cat's claw do have some potentially powerful qualities. These ingredients together are able to reduce inflammation, destroy certain viruses, and stop the spread of some cancer cells. Much more research needs to be done on this plant and its medicinal properties. Still, cat's claw ranked among the top 10 herbs sold in American natural food stores by 1997.

Plant Description

Cat's claw is a climbing shrub with thick vines growing as long as 100 feet. It is found in the Amazon rainforest and in tropical countries in South America and Central America. Much of the cat's claw available in the United States, as well as information about it, comes from Peru.

Curved, claw-like thorns grow on the stem—that's how cat's claw got its name. Bitter, water-like liquid collects inside the stem. People in South and Central America reportedly drink this on occasion to stop hunger, thirst, and fatigue.

What's It Made Of?

Cat's claw preparations are made by scraping the bark off the root of the vine. The root contains many types of plant chemicals. Some tannins also occur in the root (tannins are also found in tea). Quinovic acid glycosides help reduce inflammation and fight against some types of viruses.

Because collecting the root to get the bark kills the plant, herbalists look for other sources of these important ingredients. Right now, the inner bark of the vine seems to be a good alternative.

Available Forms

Both standardized and crude bark cat's claw are available. Crude bark is crushed and used to make tea. Standardized liquid or dried products are usually preferable: standardization is the quality control of herb manufacture.

How to Take It

Cat's claw reportedly has immune stimulant and anti-inflammatory actions. Most likely, if you or your provider have decided to add cat's claw to your daily therapy, it is probably because your immune system could use a little push or because your digestive tract is a little off kilter. You may have frequent colds or other viruses, or you may be trying to relieve irritable bowel syndrome, diverticulitis, or even Crohn's disease.

If you've decided to take cat's claw, choose between one of the preparations listed below and take as directed by your health care provider or the product packaging.

Remember that because cat's claw has not been extensively researched, it is extremely important to get it from a reputable manufacturer.

Conventional Use

For treating mild stomach pains, sore throats, and colds; immune function; and minor injuries).

  • Tea: 1 g root bark to 250 ml water, boil 10 to 5 minutes, cool, and strain. Drink 1 cup, three times daily
  • Tincture (solution made from herb and alcohol, or herb, alcohol, and water): 1 to 2 ml two to three times daily
  • Dry, encapsulated standardized extract: 20 to 60 mg daily

Precautions

The people who live where cat's claw grows say that it is very safe and nontoxic. However, until science has proven this, there are some precautions to keep in mind.

The American Herbal Products Association (AHPA) gives cat's claw a class 4 safety rating. This means that the AHPA doesn't have enough evidence to base a clear rating on. AHPA does, however, believe that the tannin content of cat's claw taken in high doses might cause some abdominal pain or gastrointestinal problems. Some researchers say that cat's claw should not be used in skin grafts or patients receiving organ transplants, or in patients with HIV, AIDS, or tuberculosis.

It is not to be used in children who are under three years of age. Breastfeeding and pregnant women also should not take cat's claw.

You might notice loose stools or diarrhea while taking cat's claw. This side effect is mild and tends to go away with continued use of cat's claw.

Possible Interactions

Cat's claw may increase the effects of some nonsteroidal anti-inflammatory drugs (NSAIDs). If you are currently taking any of these medications, consult with your health care provider before taking cat's claw.

Because cat's claw can affect your immune system, do not take this herb if you are on any immunosuppressive therapies.

Supporting Research

Aquino R, De Simone F, Pizza C, Conti C, Stein ML. Plant metabolites. Structure and in vitro activity of quinovic acid glycosides from Uncaria tomentosa and Guettarda platypoda. J Nat Prod. 1989;52:679–685.

Aquino R, De Simone F, Vincieri FF, Pizza C, Gacs-Baitz C. New polyhydroxylated triterpenes from Uncaria tomentosa. J Nat Prod. 1990;53: 559–564.

Blumenthal M, ed. The Complete German Commission E Monographs. Boston, Mass: Integrative Medicine Communications; 1998.

Blumenthal M. Herbal update: Una de gato (cat's claw): Rainforest herb gets scientific and industry attention. Whole Foods Magazine. 1995: 62–68, 78.

Blumenthal M, Riggins C. Popular Herbs in the U.S. Market: Therapeutic Monographs. Austin, Tex: The American Botanical Council; 1997.

Davis BW. A "new" world class herb for applied kinesiology practice: Uncaria tomentosa—a.k.a. Una de Gato (UDG). Collected Papers of the International College of Applied Kinesiology. 1992.

de Matta SM, Monache FD, Ferrari F, Marini-Bettolo GB. Alkaloids and procyanidine of an Uncaria sp. from Peru. Farmaco [Sci]. 1976;31:527–535.

Keplinger K, et al. Uncaria tomentosa (Willd.) DC.—ethnomedicinal use and new pharmacological, toxicological and botanical results. J Ethnopharmacol. 1999;64:23–34.

Lemaire I, et al. Stimulation of interleukin-1 and -6 production in alveolar macrophages by the neotropical liana, Uncaria tomentosa. J Ethnopharmacol. 1999;64:109–115.

Lininger S, Wright J, Austin S, Brown D, Gaby A. The Natural Pharmacy. Rocklin, Calif: Prima Health; 1998:246.

McGuffin M, Hobbs C, Upton R, Goldberg A. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, Fla: CRC Press; 1997.

Ozaki Y. Pharmacological studies of indole alkaloids obtained from domestic plants, Uncaria rhynchophylla Miq. And Amsonia elliptica Roem. et Schult. Nippon Yakurigaku Zasshi. 1989;94:17–26.

Sandoval-Chacon M, et al. Anti-inflammatory actions of cat's claw: the role of NF-kappaB. Aliment Pharmacol Ther. 1998;12:1,279–1,289.

Senatore A, Cataldo A, Iaccarino FP, Elberti MG. Phytochemical and biological study of Uncaria tomentosa. Boll Soc Ital Biol Sper. 1989;65:517–520.

Sheng Y, et al. Induction of apoptosis and inhibition of proliferation in human tumor cells treated with extracts of Uncaria tomentosa. Anticancer Res. 1998;18:3,363–3,368.

Steinberg PN. Cat's claw: medicinal properties of this Amazon vine. Nutrition Science News. 1995.

Wurm M, et al. Pentacyclic oxindole alkaloids from Uncaria tomentosa induce human endothelial cells to release a lymphocyte-proliferation-regulating factor. Planta Med. 1998;64:701–704.

Yepez AM, de Ugaz OL, Alvarez CM, De Feo V, Aquino R, De Simone F, Pizza C. Quinovic acid glycosides from Uncaria guianensis. Phytochemistry. 1991;30:1,635–1,637.


Copyright © 2000 Integrative Medicine Communications

The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. No claims or endorsements are made for any drugs or compounds currently marketed or in investigative use. This material is not intended as a guide to self-medication. The reader is advised to discuss the information provided here with a doctor, pharmacist, nurse, or other authorized healthcare practitioner and to check product information (including package inserts) regarding dosage, precautions, warnings, interactions, and contraindications before administering any drug, herb, or supplement discussed herein.

           
                                                    

                         

                                

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