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  Trandolapril and Verapamil

Trandolapril and Verapamil

Pronunciation

(tran DOE la pril & ver AP a mil)

Brand Names

Tarkaź

Therapeutic Categories

Angiotensin-Converting Enzyme (ACE) Inhibitor Combination; Antihypertensive Agent, Combination

What is this medicine used for?

  • This medicine is used to treat high blood pressure.

How does it work?

  • Verapamil blocks certain channels in blood vessels that cause a relaxation and a lowering of blood pressure.
  • Trandolapril lowers blood pressure by decreasing production of a strong chemical in the body that increases blood pressure.

How is it best taken?

  • Take with or without food. Take with food if this medicine causes an upset stomach.
  • Swallow whole. Do not chew, break, or crush.
  • Take at a similar time every day.

What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.
  • There should be an interval of 24 hours between doses.
  • Do not change dose or stop taking medicine without talking with healthcare provider.

What are the precautions when taking this medicine?

  • Wear disease medical alert identification for high blood pressure.
  • Limit alcohol intake (includes wine, beer, and liquor). Can increase blood pressure.
  • Avoid potassium-containing salt substitutes and potassium supplements. Talk with healthcare provider.
  • Do not use over-the-counter products that increase blood pressure. These include cough or cold remedies, diet pills, stimulants, ibuprofen or like products, and certain herbs or supplements. Talk with healthcare provider.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Do not use in pregnancy and do not get pregnant. Use birth control that you can trust while taking this medicine.
  • Tell healthcare provider if you are breast-feeding.

What are the common side effects of this medicine?

  • Lightheaded. Avoid driving, doing other tasks or hobbies that require you to be alert until you see how this medicine affects you.
  • Dizziness is common. Rise slowly over several minutes from sitting or lying position. Be careful climbing stairs.
  • Headache. Mild pain medicine may help.
  • Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.
  • Abnormal taste (metallic, salty, or none). This is usually reversible.
  • Fluid accumulation usually as ankle swelling.
  • Dry cough.

What should I monitor?

  • Check blood pressure regularly.
  • Follow diet plan (low salt) and exercise program as recommended by healthcare provider.
  • Check blood work. Talk with healthcare provider.
  • Follow up with healthcare provider.

Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Severe headaches.
  • Passing out, fainting, dizziness, or lightheadedness.
  • Excessive sweating, dehydration, vomiting, or diarrhea. May lead to low blood sugar.
  • Significant, persistent cough.
  • Any rash.

How should I store this medicine?

  • Store in a tight, light-resistant container at room temperature. Protect from moisture.

General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your (prescription, herbal/supplements, vitamins, over-the-counter) medicines with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).

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