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Rosiglitazone
Rosiglitazone
Pronunciation
(roe si GLI ta zone)
Brand Names
Avandiaź
Therapeutic Categories
Hypoglycemic Agent, Oral; Thiazolidinedione Derivative
What is this medicine used for?
- This medicine lowers blood sugar in type II diabetics. It can be used alone
or in combination with other diabetes medicine. It may take up to 3 months to
see the full effect.
How does it work?
- Rosiglitazone increases insulin activity in the body.
How is it best taken?
- Take with or without food. Take with food if this medicine causes an upset
stomach.
- Take at a similar time every day.
- Follow diet plan and exercise program as recommended by healthcare
provider.
What do I do if I miss a dose?
- Take a missed dose as soon as possible.
- If it is missed at the usual meal, take it with the next meal.
- Do not take a double dose or extra doses.
What are the precautions when taking this
medicine?
- Wear disease medical alert identification for diabetes.
- Do not use if you have liver disease. Talk with healthcare provider.
- Use caution if you have high cholesterol (increases bad cholesterol). Talk
with healthcare provider.
- Use caution if you have a weakened heart. May cause water weight gain. Talk
with healthcare provider.
- Watch for weight gain.
- Tell healthcare provider if you are allergic to any medicine. Make sure to
tell about the allergy and how it affected you. This includes telling about
rash; hives; itching; shortness of breath; wheezing; cough; swelling of face,
lips, tongue, throat; or any other symptoms involved.
- This medicine can cause ovulation in premenopausal women who have not been
ovulating. Birth control may need to be considered.
- Tell healthcare provider if you are pregnant or plan on getting pregnant.
- Tell healthcare provider if you are breast-feeding.
What are the common side effects of this
medicine?
- Weight gain.
- Increased cholesterol (increase of 10% to 15%).
What should I monitor?
- Check blood sugar as ordered by healthcare provider. Call if glucose is
less than 80 mg/dL or greater than 250 mg/dL. Bring results to follow-up visits.
- Watch for low blood sugar. Causes anger, shaking, rapid heartbeats,
confusion, sweating.
- Watch for high blood sugar. Causes many trips to the bathroom, thirst, and
weight loss.
- Check blood work. Talk with healthcare provider.
- Follow diet plan and exercise program as recommended by healthcare
provider.
- Have an eye exam and visit to the foot doctor every year.
- Liver function tests need monitoring before therapy and then every 2 months
for the first year and periodically after that. Talk with healthcare provider.
- Check lipid (cholesterol) panel. Talk with healthcare provider.
Reasons to call healthcare provider
immediately
- Signs of a life-threatening reaction. These include wheezing; tightness in
the chest; fever; itching; bad cough; blue skin color; fits; swelling of face,
lips, tongue, or throat.
- Low blood sugar or very high blood sugar.
- Nausea, vomiting, belly pain, feeling tired, dark urine, yellow eyes/skin,
not hungry.
- Any rash.
How should I store this medicine?
- Store in a tight container at room temperature.
General statements
- Do not share your medicine with others and do not take anyone else's
medicine.
- Keep all medicine out of the reach of children and pets.
- Keep a list of all your medicines (prescription, herbal/supplements,
vitamins, over-the-counter) with you. Give this list to healthcare provider
(doctor, nurse, pharmacist, physician assistant)
- Talk with healthcare provider before starting any new medicine, including
over-the-counter or natural products (herbs, vitamins).
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