Mirtazapine

Pronunciation

Brand Names

Therapeutic Categories

What is this medicine used for?

• This medicine is used for the treatment of depression.

How does it work?

• Mirtazapine increases concentrations of chemicals in the brain. Sleep and appetite may improve quickly. Other depressive symptoms may take up to 4-6 weeks to improve.

How is it best taken?

• Take with or without food. Take with food if this medicine causes an upset stomach.
• Do not suddenly stop using this medicine if you have been taking it for a long time. Medicine should be slowly decreased.
• May take at bedtime if it causes you to feel too sleepy.

What do I do if I miss a dose?

• Take a missed dose as soon as possible.
• If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
• Do not take a double dose or extra doses.

What are the precautions when taking this medicine?

• If you are 65 or older, you may have more side effects. You could feel sleepy and shaky.
• You may not be alert. Avoid driving, doing other tasks or hobbies until you see how this medicine affects you.
• Avoid alcohol (includes wine, beer, and liquor) and other medicines that slow your actions and reactions. This includes sedatives, tranquilizers, mood stabilizers, or pain medicine. Talk with healthcare provider.
• Do not use monamine oxidase inhibitors (isocarboxazid, phenelzine, or tranylcypromine) while taking this medicine. Separate use by 2 weeks.
• Make sure to get good dental care. You are at higher risk of cavities.
• You can get sunburned more easily. Avoid lots of sun. Use sunscreen; wear protective clothing and eyewear.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes rash; hives; itching; difficulty breathing; wheezing; cough; swelling of lips, tongue, throat; or any other symptoms involved.
• Tell healthcare provider if you are pregnant or plan on getting pregnant.
• Tell healthcare provider if you are breast-feeding.

What are the common side effects of this medicine?

• Feeling sleepy or lightheaded. Avoid driving, doing other tasks or hobbies that require you to be alert until you see how this medicine affects you.
• Dizziness is common. Rise slowly over several minutes from sitting or lying position. Be cautious climbing stairs.
• Dry mouth. Frequent mouth care, sucking hard candy, or chewing gum may help.
• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.
• Weight gain.

What should I monitor?

• Check lipid (cholesterol) panel (blood test). Talk with healthcare provider.
• Follow up with healthcare provider.

Reasons to call healthcare provider immediately

• Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
• Changes in thinking clearly and logically.
• Too tired or sleepy.
• Passing out, fainting, dizziness, or lightheadedness.
• Any rash.
• No improvement in condition or feeling worse.

How should I store this medicine?

• Store in a tight container at room temperature.

General statements

• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant)
• Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).

Copyright © 1978-2000 Lexi-Comp Inc. All Rights Reserved