Doxepin

Pronunciation

Brand Names

Canadian/Mexican Brand Names

Therapeutic Categories

What is this medicine used for?

• This medicine is used for the treatment of depression, anxiety disorders, obsessive and compulsive symptoms, panic disorder, eating disorders, and chronic pain conditions.
• It is also used to prevent migraine headaches and bedwetting in children.
• The cream is used to treat itching.

How does it work?

• Doxepin increases chemicals in the brain. Sleep and appetite may improve quickly. Other depressive symptoms may take up to 4-6 weeks to improve. It blocks the cause of the itch.

How is it best taken?

Oral:

• Take with or without food. Take with food if this medicine causes an upset stomach.
• Do not suddenly stop using this medicine if you have been taking it for a long time. Medicine should be slowly decreased.
• May take at bedtime if it causes too much drowsiness.
• A liquid (concentrate) is available if you cannot swallow pills. Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given.

Skin:

• Do not take by mouth. For skin only. Keep out of mouth, nose, and eyes (may burn).
• Use a small amount over the area affected as a light film. Run in gently.
• Do not put coverings (bandages, dressings, make-up) over the area unless told to do so by healthcare provider.

What do I do if I miss a dose?

Oral:

• Take a missed dose as soon as possible.
• If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
• Do not take a double dose or extra doses.

Topical:

• This medicine can be used on an as needed basis.

What are the precautions when taking this medicine?

• If you are 65 or older, you have more side effects. Feeling sleepy, dizzy, or lightheaded could be dangerous. There are other choices if this medicine is too strong for you.
• You may not be alert. Avoid driving, doing other tasks or hobbies until you see how this medicine affects you.
• Avoid alcohol (includes wine, beer, and liquor) and other medicines that slow your actions and reactions. This includes sedatives, tranquilizers, mood stabilizers, or pain medicine. Talk with healthcare provider.
• Make sure to get good dental care. You may have a higher risk for cavities.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
• Tell healthcare provider if you are pregnant or plan on getting pregnant.
• Tell healthcare provider if you are breast-feeding.

What are the common side effects of this medicine?

• Feeling sleepy, lightheaded, or having blurred vision. Avoid driving, doing other tasks or hobbies that require you to be alert until you see how this medicine affects you.
• Dizziness is common. Rise slowly over several minutes from sitting or lying position. Be careful climbing stairs.
• Dry mouth. Frequent mouth care, sucking hard candy, or chewing gum may help.
• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.
• Unable to pass urine. Go to the bathroom before taking medicine. Talk with healthcare provider if it becomes a problem.

What should I monitor?

• Follow up with healthcare provider.

Reasons to call healthcare provider immediately

• Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
• Changes in thinking clearly and logically.
• Too tired or sleepy.
• Passing out, fainting, dizziness, or lightheadedness.
• Any rash.
• No improvement in condition or feeling worse.

How should I store this medicine?

• Store in a tight container at room temperature.

General statements

• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant)
• Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).

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