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  Dipyridamole

Dipyridamole

Pronunciation

(dye peer ID a mole)

Brand Names

Persantine®

Canadian/Mexican Brand Names

Apo®-Dipyridamole FC (Canada); Apo®-Dipyridamole SC (Canada); Asasantine®[with Aspirin also] (Canada); Novo-Dipiradol® (Canada); Dirinol (Mexico); Lodimol® (Mexico); Trompersantin® (Mexico)

Therapeutic Categories

Antiplatelet Agent; Vasodilator, Coronary

What is this medicine used for?

  • This medicine can be used in combination with a blood thinner called warfarin to prevent clots after a heart valve is replaced.
  • Another use includes stroke prevention and keeping grafts opened after heart bypass surgery. Medicine works best if used with aspirin.

How does it work?

  • Dipyridamole prevents platelets from becoming sticky and clumping together. It also dilates blood vessels.

How is it best taken?

  • Take with or without food. Take with food if this medicine causes an upset stomach.

What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.

What are the precautions when taking this medicine?

  • Avoid alcohol (includes wine, beer, and liquor).
  • If you have had a stomach ulcer or bleeding tell healthcare provider.
  • Avoid ibuprofen or like products, other blood thinners (warfarin, ticlopidine, clopidogrel), garlic, ginseng, ginkgo, vitamin E. Talk with healthcare provider.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Tell healthcare provider if you are breast-feeding.

What are the common side effects of this medicine?

  • Headache. Mild pain medicine may help.
  • Belly pain and cramps.

What should I monitor?

  • Follow up with healthcare provider.

Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Numbness, tingling, weakness on one side greater than the other, difficulty speaking, or blurred vision.

How should I store this medicine?

  • Store in a tight container at room temperature.

General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).

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