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Diethylstilbestrol
Diethylstilbestrol
Pronunciation
(dye eth il stil BES trole)
Brand Names
Stilphostrol®
Canadian/Mexican Brand Names
Honvol® (Canada)
Therapeutic Categories
Estrogen Derivative; Estrogen Derivative, Oral; Estrogen Derivative, Parenteral
What is this medicine used for?
- This medicine can be used to treat inoperable, progressing prostate
cancer.
How does it work?
- Diethylstilbestrol competes with testosterone to slow the growth of the
cancer.
How is it best taken?
- Take with or without food. Take with food if this medicine causes an upset
stomach or take as directed by your healthcare provider.
What do I do if I miss a dose?
- Take a missed dose as soon as possible.
- If it is almost time for the next dose, skip the missed one. Return to your
regular schedule.
- Do not take a double dose or extra doses.
- Do not change dose or stop taking medicine without talking with healthcare
provider.
What are the precautions when taking this
medicine?
- Limit alcohol intake (includes wine, beer, and liquor).
- Do not use if you have had breast cancer.
- Not to be taken by women.
- Use caution if you have a weakened heart or high blood pressure. Talk with
healthcare provider.
- Tell healthcare provider if you have ever had any blood circulation
problems or clots in your legs, arms, or lungs.
- Tell healthcare provider if you are allergic to any medicine. Make sure to
tell about the allergy and how it affected you. This includes telling about
rash; hives; itching; shortness of breath; wheezing; cough; swelling of face,
lips, tongue, throat; or any other symptoms involved.
What are the common side effects of this
medicine?
- Headache. Mild pain medicine may help.
- Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard
candy, or chewing gum may help.
- Belly pain and cramps.
- Breast enlargement/tenderness.
What should I monitor?
- Check blood pressure and heart rate (pulse) regularly.
Reasons to call healthcare provider
immediately
- Signs of a life-threatening reaction. These include wheezing; tightness in
the chest; fever; itching; bad cough; blue skin color; fits; swelling of face,
lips, tongue, or throat.
- Severe headache.
- Severe nausea, vomiting, and/or diarrhea.
- Swelling/pain of a leg or arm, sudden shortness of breath, difficulty
breathing, chest pain.
- A lump in the breast.
- Any rash.
How should I store this medicine?
- Store in a dry place at room temperature.
General statements
- Do not share your medicine with others and do not take anyone else's
medicine.
- Keep all medicine out of the reach of children and pets.
- Keep a list of all your medicines (prescription, herbal/supplements,
vitamins, over-the-counter) with you. Give this list to healthcare provider
(doctor, nurse, pharmacist, physician assistant).
- Read the package insert for more details (given with the medicine).
- Talk with healthcare provider before starting any new medicine, including
over-the-counter or natural products (herbs, vitamins).
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