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Clorazepate
Clorazepate
Pronunciation
(klor AZ e pate)
Brand Names
Gen-XENE®; Tranxene®
Canadian/Mexican Brand Names
Apo-Clorazepate® (Canada); Novo-Clopate (Canada)
Therapeutic Categories
Anticonvulsant; Benzodiazepine; Sedative
What is this medicine used for?
- This medicine is used in the treatment of anxiety, alcohol withdrawal, and
seizures.
How does it work?
- Clorazepate works in the brain at the emotional center called the limbic
system.
How is it best taken?
- Take with or without food. Take with food if this medicine causes an upset
stomach.
- Tablet may be crushed and mixed with food or liquid.
- Do not suddenly stop using this medicine if you have been taking it for a
long time. Medicine should be slowly decreased.
What do I do if I miss a dose?
- Take a missed dose as soon as possible.
- If it is almost time for the next dose, skip the missed one. Return to your
regular schedule.
- Since this medicine is frequently taken on an as needed basis, separate
dose by 6-12 hours.
What are the precautions when taking this
medicine?
- Check medicines with healthcare provider. This medicine may not mix well
with other medicines.
- This medicine may be habit-forming with long-term use.
- If you are 65 or older, you may have more side effects. You could feel
sleepy and shaky.
- You may not be alert. Avoid driving, doing other tasks or hobbies until you
see how this medicine affects you.
- Avoid alcohol (includes wine, beer, and liquor) and other medicines that
slow your actions and reactions. This includes sedatives, tranquilizers, mood
stabilizers, or pain medicine. Talk with healthcare provider.
- Tell healthcare provider if you have lung disease. You may be more
sensitive to this medicine.
- Tell healthcare provider if you are allergic to any medicine. Make sure to
tell about the allergy and how it affected you. This includes telling about
rash; hives; itching; shortness of breath; wheezing; cough; swelling of face,
lips, tongue, throat; or any other symptoms involved.
- Do not use in pregnancy and do not get pregnant. Use birth control that you
can trust while taking this medicine.
- Do not use if you are breast-feeding.
What are the common side effects of this
medicine?
- Feeling sleepy, lightheaded, unable to think clearly, or having blurred
vision. Avoid driving, doing other tasks or hobbies that require you to be alert
until you see how this medicine affects you.
- Dry mouth. Frequent mouth care, sucking hard candy, or chewing gum may
help.
What should I monitor?
- Watch for change in symptoms. Is condition better, worse, or about the
same?
Reasons to call healthcare provider
immediately
- Signs of a life-threatening reaction. These include wheezing; tightness in
the chest; fever; itching; bad cough; blue skin color; fits; swelling of face,
lips, tongue, or throat.
- Changes in balance, feeling shaky or unsteady.
- Too tired or sleepy.
- Any rash.
How should I store this medicine?
- Store in a tight container at room temperature.
General statements
- Do not share your medicine with others and do not take anyone else's
medicine.
- Keep all medicine out of the reach of children and pets.
- Keep a list of all your medicines (prescription, herbal/supplements,
vitamins, over-the-counter) with you. Give this list to healthcare provider
(doctor, nurse, pharmacist, physician assistant)
- Talk with healthcare provider before starting any new medicine, including
over-the-counter or natural products (herbs, vitamins).
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