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  Clonidine

Clonidine

Pronunciation

(KLOE ni deen)

Brand Names

Catapres® Oral; Catapres-TTS® Transdermal; Duraclon™ Injection

Canadian/Mexican Brand Names

Apo-Clonidine® (Canada); Catapresan-100® (Mexico); Dixarit® (Canada); Novo-Clonidine (Canada); Nu-Clonidine (Canada)

Therapeutic Categories

Alpha2-Adrenergic Agonist Agent; Antihypertensive Agent; Antimigraine Agent

What is this medicine used for?

  • This medicine is used to treat high blood pressure, prevent migraine headache, treat menopausal flushing and painful menstruation (periods).
  • It offers pain control in combination with narcotics when infused into the spine area.
  • It has also been used to treat drug abuse and drug withdrawal syndromes (cocaine, narcotics, cigarette smoking).
  • Rarely, it is used for the treatment of diabetes-associated diarrhea.

How does it work?

  • Clonidine decreases the body's release of adrenaline and other hormones that increase blood pressure, heart rate, and anxiety.
  • Pain control works by preventing the pain signal's transmission to the brain.

How is it best taken?

  • Follow diet plan (low salt) as recommended by healthcare provider if you are taking this medicine for high blood pressure.
  • Do not suddenly stop using this medicine. Medicine should be slowly decreased. High blood pressure can worsen.

Tablet:

  • Take with or without food. Take with food if this medicine causes an upset stomach. Take last dose of the day at bedtime.
  • Do not suddenly stop using this medicine. Medicine should be slowly decreased. High blood pressure can worsen.

Skin patch:

  • Remove old patch first.
  • Use on clean, dry skin. Move site with each new patch. Use on trunk of body. This includes chest, back, and belly.
  • If patch loosens during the week, apply tape directly over it to hold it in place.

What do I do if I miss a dose?

  • Do not take a double dose or extra doses.
  • Do not change dose or stop taking medicine without talking with healthcare provider.

Tablet:

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.

Skin patch:

  • Apply the missed patch as soon as possible after removing the old one.
  • If it is almost time for the next patch, place the new patch on immediately and keep it on for 7 days.
  • Start new schedule from time patch is replaced.

What are the precautions when taking this medicine?

  • Wear disease medical alert identification for high blood pressure.
  • If you are 65 or older, you may have more side effects. You could feel sleepy.
  • You may not be alert. Avoid driving, doing other tasks or hobbies until you see how this medicine affects you.
  • Avoid alcohol (includes wine, beer, and liquor) and other medicines that slow your actions and reactions. This includes sedatives, tranquilizers, mood stabilizers, or pain medicine. Talk with healthcare provider.
  • Do not use over-the-counter products that increase blood pressure. These include cough or cold remedies, diet pills, stimulants, ibuprofen or like products, and certain herbs or supplements. Talk with healthcare provider.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Tell healthcare provider if you are breast-feeding.

What are the common side effects of this medicine?

  • Feeling sleepy or unable to think clearly. Avoid driving, doing other tasks or hobbies that require you to be alert until you see how this medicine affects you.
  • Dizziness is common. Rise slowly over several minutes from sitting or lying position. Be careful climbing stairs.
  • Dry mouth. Frequent mouth care, sucking hard candy, or chewing gum may help.
  • Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.

What should I monitor?

  • Check blood pressure and heart rate (pulse) regularly.
  • Follow diet plan and exercise program as recommended by healthcare provider.

Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Too tired or sleepy.
  • Passing out, fainting, dizziness, or lightheadedness.
  • Any rash.

How should I store this medicine?

  • Store tablets in a tight, light-resistant container at room temperature.
  • Store skin patch at room temperature.

General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant)
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).

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