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Chlorpromazine
Chlorpromazine
Pronunciation
(klor PROE ma zeen)
Brand Names
Ormazine; Thorazine®
Canadian/Mexican Brand Names
Apo-Chlorpromazine® (Canada); Chlorprom® (Canada); Chlorpromanyl® (Canada);
Largactil® (Canada); Novo-Chlorpromazine® (Canada)
Therapeutic Categories
Antiemetic; Antipsychotic Agent; Phenothiazine Derivative
What is this medicine used for?
- This medicine is used for the treatment of symptoms seen in schizophrenia.
It may take weeks to see the benefits.
- It is also used for the treatment of nausea and vomiting.
- Other uses include treatment of Tourette's disorder, hiccups, mania,
behavioral problems in children, behavior problems of dementia in the elderly,
and treatment of disabling involuntary movements in Huntington's chorea.
How does it work?
- Chlorpromazine changes a variety of chemicals in the brain.
How is it best taken?
- Take with or without food. Take with food if this medicine causes an upset
stomach.
- A liquid (syrup, concentrate) is available if you cannot swallow pills.
Those who have feeding tubes can also use the syrup. Do not use concentrate with
feeding tubes. Flush the feeding tube before and after medicine is given. Mix
concentrate with 1/2
a cup of water or soft food before drinking or eating.
- Swallow sustained-release capsule whole. Do not chew, break, or crush.
- Use suppository rectally only.
- Make sure you are drinking enough liquids unless told to drink less by
healthcare provider. Avoid products with caffeine.
- Do not suddenly stop using this medicine if you have been taking it for a
long time. Medicine should be slowly decreased.
- Do not spill liquid concentrate on skin. Can irritate your skin.
What do I do if I miss a dose?
- Take a missed dose as soon as possible.
- If it is almost time for the next dose, skip the missed one. Return to your
regular schedule.
- Do not take a double dose or extra doses.
What are the precautions when taking this
medicine?
- If you are 65 or older, you may have more side effects.
- You may not be alert. Avoid driving, doing other tasks or hobbies until you
see how this medicine affects you.
- Avoid alcohol (includes wine, beer, and liquor) and other medicines that
slow your actions and reactions. This includes sedatives, tranquilizers, mood
stabilizers, or pain medicine. Talk with healthcare provider.
- Be careful in hot weather. You may be more sensitive to the heat.
- You can get sunburned more easily. Avoid lots of sun. Use sunscreen; wear
protective clothing and eyewear.
- Tell healthcare provider if you are allergic to any medicine. Make sure to
tell about the allergy and how it affected you. This includes telling about
rash; hives; itching; shortness of breath; wheezing; cough; swelling of face,
lips, tongue, throat; or any other symptoms involved.
- Tell healthcare provider if you are pregnant or plan on getting pregnant.
- Do not use if you are breast-feeding.
What are the common side effects of this
medicine?
- Feeling sleepy, lightheaded, or having blurred vision. Avoid driving, doing
other tasks or hobbies that require you to be alert until you see how this
medicine affects you.
- Dizziness is common. Rise slowly over several minutes from sitting or lying
position. Be careful climbing stairs.
- Dry mouth. Frequent mouth care, sucking hard candy, or chewing gum may
help.
- Constipation. More liquids, regular exercise, or a fiber-containing diet
may help. Talk with healthcare provider about a stool softener or laxative.
- Unable to pass urine. Go to the bathroom before taking medicine. Talk with
healthcare provider if it becomes a problem.
- Movements not controlled by you, shakiness, difficulty moving around, or
stiffness.
- Restlessness and inability to stay still or calm.
- Weight gain.
- Change in sexual ability or desire. This can return to normal after
medicine stopped. Talk with healthcare provider about other medicines without
this side effect.
What should I monitor?
- Monitor for side effects.
- Follow up with healthcare provider.
Reasons to call healthcare provider
immediately
- Signs of a life-threatening reaction. These include wheezing; tightness in
the chest; fever; itching; bad cough; blue skin color; fits; swelling of face,
lips, tongue, or throat.
- Movements not controlled by you, shakiness, difficulty moving around, or
stiffness.
- Restlessness and inability to stay still or calm.
- Changes in balance, feeling shaky or unsteady.
- Too tired or sleepy.
- Passing out, fainting, dizziness, or lightheadedness.
- Menstrual changes. This includes lots of bleeding, spotting, or bleeding
between cycles.
- Any rash.
- No improvement in condition or feeling worse.
How should I store this medicine?
- Store in a tight, light-resistant container at room temperature.
General statements
- Do not share your medicine with others and do not take anyone else's
medicine.
- Keep all medicine out of the reach of children and pets.
- Keep a list of all your medicines (prescription, herbal/supplements,
vitamins, over-the-counter) with you. Give this list to healthcare provider
(doctor, nurse, pharmacist, physician assistant).
- Talk with healthcare provider before starting any new medicine, including
over-the-counter or natural products (herbs, vitamins).
Copyright © 1978-2000 Lexi-Comp Inc. All Rights Reserved
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