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  Chlorpheniramine and Phenylpropanolamine

Chlorpheniramine and Phenylpropanolamine

Pronunciation

(klor fen IR a meen & fen il proe pa NOLE a meen)

Brand Names

Allerest® 12 Hour Capsule [OTC]; A.R.M.® Caplet [OTC]; Chlor-Rest® Tablet [OTC]; Demazin® Syrup [OTC]; Genamin® Cold Syrup [OTC]; Ornade® Spansule®; Resaid®; Rescon Liquid [OTC]; Silaminic® Cold Syrup [OTC]; Temazin® Cold Syrup [OTC]; Thera-Hist® Syrup [OTC]; Triaminic® Allergy Tablet [OTC]; Triaminic® Cold Tablet [OTC]; Triaminic® Syrup [OTC]; Tri-Nefrin® Extra Strength Tablet [OTC]; Triphenyl® Syrup [OTC]

Therapeutic Categories

Antihistamine/Decongestant Combination

What is this medicine used for?

  • This medicine relieves symptoms (runny nose, sneezing, throat irritation and itching; watery, irritated, itchy, red eyes) from allergies.
  • Long-term nasal congestion and headache are treated by phenylpropanolamine.

How does it work?

  • Chlorpheniramine, if taken before coming in contact with the material that causes the allergy, blocks the allergic reaction by minimizing/preventing the body's reaction to the allergen.
  • Phenylpropanolamine shrinks swollen nasal tissue and opens up passages. Sinus drainage is increased by this.

How is it best taken?

  • Take with or without food. Take with food if this medicine causes an upset stomach.
  • This medicine is most effective if started before contact with the allergen. Take at least 1-3 hours before.
  • Swallow sustained-release capsule/tablet whole. Do not chew, break, or crush.
  • A liquid (syrup) is available if you cannot swallow pills. Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given.
  • Make sure you are drinking enough liquids unless told to drink less by healthcare provider. Avoid products with caffeine.

What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • This medicine is often taken on an as needed basis.
  • Do not take a double dose or extra doses.

What are the precautions when taking this medicine?

  • Wear disease medical alert identification for allergies.
  • Avoid alcohol (includes wine, beer, and liquor) and other medicines that slow your actions and reactions. This includes sedatives, tranquilizers, mood stabilizers, or pain medicine. Talk with healthcare provider.
  • Limit caffeine (teas, coffee, colas) and chocolate intake. Use may increase inability to sleep or cause nervousness with this medicine.
  • Use caution if you have high blood pressure. Talk with healthcare provider.
  • Use caution if you have liver disease. Talk with healthcare provider.
  • Increased activity or insomnia may be seen in children.
  • Do not use over-the-counter products that increase blood pressure. These include cough or cold remedies, diet pills, stimulants, ibuprofen or like products, and certain herbs or supplements. Talk with healthcare provider.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Do not use if you are breast-feeding.

What are the common side effects of this medicine?

  • Dry mouth. Frequent mouth care, sucking hard candy, or chewing gum may help.
  • Dizziness. Avoid driving, doing other tasks or hobbies that require you to be alert until you see how this medicine affects you.
  • Inability to sleep, nervousness, excitability, and restlessness.

What should I monitor?

  • Check effectiveness of medicine in preventing or treating symptoms.

Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Chest pains, fast heartbeats, passing out, fainting, or severe headache.
  • Too tired or sleepy.
  • Any rash.
  • No improvement in condition or feeling worse.

How should I store this medicine?

  • Store in a tight, light-resistant container at room temperature.

General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).

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