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Chlorotrianisene
Chlorotrianisene
Pronunciation
(klor oh trye AN i seen)
Brand Names
TACE®
Therapeutic Categories
Estrogen Derivative, Oral
What is this medicine used for?
- This medicine is used to stop/reduce the symptoms of menopause, especially
hot flashes, vaginal dryness, itching, and burning.
- It is used to treat female hypogonadism.
- Rarely, it is used for the treatment of prostate cancer.
How does it work?
- After menopause, when the body no longer produces estrogen,
chlorotrianisene is used as a simple replacement of estrogen.
How is it best taken?
- Take with food at a similar time every day or as directed by your
healthcare provider. There may be days when you will not take the medicine.
What do I do if I miss a dose?
- Take a missed dose as soon as possible.
- If it is almost time for the next dose, skip the missed one. Return to your
regular schedule.
- Do not take a double dose or extra doses.
- Do not change dose or stop taking medicine without talking with healthcare
provider.
What are the precautions when taking this
medicine?
- This medicine does not treat depression or nervous problems.
- Limit alcohol intake (includes wine, beer, and liquor). May increase risk
of breast cancer.
- Do not use if you have unusual vaginal bleeding that has not been examined
by healthcare provider.
- Use caution if you have a weakened heart or high blood pressure. Talk with
healthcare provider.
- Tell your healthcare provider if you have ever had any blood clots in your
legs, arms, or lungs.
- There may be a higher risk of endometrial/breast cancer. Talk with
healthcare provider.
- Do not use if you have had breast or uterine cancer or if someone in your
family (sister, mother, aunt) has had breast cancer. Talk with healthcare
provider.
- Do not take if allergic to the dye tartrazine (yellow). This is seen more
often in people allergic to aspirin.
- Tell healthcare provider if you are allergic to any medicine. Make sure to
tell about the allergy and how it affected you. This includes telling about
rash; hives; itching; shortness of breath; wheezing; cough; swelling of face,
lips, tongue, throat; or any other symptoms involved.
- Do not use in pregnancy and do not get pregnant. Use birth control that you
can trust during use of this medicine and for 1 month after stopping it.
- Do not use if you are breast-feeding.
What are the common side effects of this
medicine?
- Headache. Mild pain medicine may help.
- Belly pain and cramps.
- Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard
candy, or chewing gum may help.
- Breast enlargement/tenderness.
- For women, vaginal bleeding (breakthrough bleeding, spotting) may occur.
- Change in sexual ability or desire. This can return to normal after
medicine is stopped. Talk with healthcare provider about other medicines without
this side effect.
What should I monitor?
- For women, periodic breast (monthly self-exams) and gynecologic exams are
important.
- Follow diet plan (calcium and vitamin D supplementation) and exercise
program as recommended by healthcare provider.
- Follow up with healthcare provider at least every year. Talk about duration
of treatment.
Reasons to call healthcare provider
immediately
- Signs of a life-threatening reaction. These include wheezing; tightness in
the chest; fever; itching; bad cough; blue skin color; fits; swelling of face,
lips, tongue, or throat.
- Severe headache.
- For women, unusual vaginal bleeding. This includes lots of bleeding,
spotting, or bleeding between cycles.
- Severe nausea, vomiting, and/or diarrhea.
- Any rash.
- Swelling/pain of a leg or arm, sudden shortness of breath, difficulty
breathing, chest pain.
- A lump in the breast.
- Any rash.
How should I store this medicine?
- Store in a dry place at room temperature.
General statements
- Do not share your medicine with others and do not take anyone else's
medicine.
- Keep all medicine out of the reach of children and pets.
- Keep a list of all your medicines (prescription, herbal/supplements,
vitamins, over-the-counter) with you. Give this list to healthcare provider
(doctor, nurse, pharmacist, physician assistant).
- Read the package insert for more details (given with the medicine).
- Talk with healthcare provider before starting any new medicine, including
over-the-counter or natural products (herbs, vitamins).
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