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  Amprenavir

Amprenavir

Pronunciation

(am PRE na veer)

Brand Names

Agenerase™

Therapeutic Categories

Antiretroviral Agent, Protease Inhibitor; Protease Inhibitor

What is this medicine used for?

  • This medicine is used to treat HIV infection. It is usually taken with 2 other medicines.

How does it work?

  • Amprenavir stops the HIV virus from increasing. It binds up an enzyme that is needed for reproduction of the virus.

How is it best taken?

  • The medicine must be taken exactly as directed.
  • Take with or without food. Take with food if this medicine causes an upset stomach. Avoid a high-fat meal.
  • A liquid (solution) is available if you cannot swallow pills. Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine administration.
  • Avoid grapefruit or grapefruit juice.
  • Do not take didanosine (DDI) or antacids within 1 hour of this medicine.

What do I do if I miss a dose?

  • If you miss a dose by less than 4 hours then take it now.
  • If you miss a dose by more than 4 hours then skip the missed dose.
  • Return to your regular schedule for the next dose.
  • Do not take a double dose or extra doses.
  • Do not change dose or stop taking medicine without talking with healthcare provider.

What are the precautions when taking this medicine?

  • Check medicines with healthcare provider. This medicine may not mix well with many other medicines.
  • Do not run out of this medication. Get it refilled today!
  • Do not take extra vitamin E supplement. Vitamin E is already included in this medicine.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Protect against sexual spread of disease. Use an effective method of birth control. Talk with healthcare provider if you have questions.
  • Do not use in pregnancy and do not get pregnant. Use birth control that you can trust while taking this medicine.
  • Breast-feeding is not recommended in HIV disease.

What are the common side effects of this medicine?

  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Diarrhea.
  • Numbness and tingling of the mouth and around the mouth.
  • Rash.

What should I monitor?

  • Check blood work. Talk with healthcare provider.
  • Follow up with healthcare provider.

Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Severe nausea, vomiting, and/or diarrhea.
  • Any rash.
  • No improvement in condition or feeling worse.

How should I store this medicine?

  • Store in a tight container at room temperature.

General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).

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