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Cancer, Colorectal

Colorectal cancer, or cancer of the colon or rectum, is the second leading cause of cancer-related death in the United States today, affecting both men and women. There are about 160,000 cases of colorectal cancer diagnosed in the U.S. each year, with most cases occurring in people over 60 years of age. The tumor is extremely slow-growing, taking 10 to 20 years to become malignant.

Signs and Symptoms

Colorectal cancer is often accompanied by the following signs and symptoms.

bulletChange in usual bowel habits with less stool
bulletBleeding from the rectum
bulletAbdominal swelling or pain
bulletNausea and vomiting
bulletAnemia and loss of strength

What Causes It?

A poor diet (high in fats and low in fiber), the environment, and genetics are considered likely causes of colorectal cancer.

Who's Most At Risk?

The following risk factors increase a person's chances of developing colorectal cancer.

bulletAge—Colorectal cancer most commonly affects people 50 years and older, with the risk increasing with age.
bulletLifestyle habits—A diet high in fat and low in fiber, alcohol use, and current or past smoking.
bulletPolyps—These benign, precancerous growths on the inner wall of the colon and rectum can become cancerous if not removed.
bulletPersonal medical history of certain cancers—Women with a history of cancer of the ovary, uterus, or breast have a somewhat increased risk. Also, a person who has already had colorectal cancer may develop it a second time.
bulletFamily medical history of colorectal cancer—First-degree relatives of a person who has had colorectal cancer are somewhat more likely to develop this disease, particularly if many family members have had it.
bulletUlcerative colitis—Having this condition, in which the lining of the colon becomes inflamed, may increase a person's risk.

What to Expect at Your Provider's Office

Whether or not you are in a high-risk group, if you are experiencing symptoms associated with colorectal cancer, you should see your health care provider for an exam. While patients often find the exam uncomfortable or even embarrassing, it is essential for diagnosing and treating this disease. Laboratory tests may be done on your blood or stool, and, if you are diagnosed with colorectal cancer, you may be sent for a CT scan and chest radiography to check if the cancer has spread to other organs.

Treatment Options

Prevention

Early detection, removal of polyps, and following a high-fiber, low-fat diet may reduce your chances of developing colorectal cancer or may prevent its growth or spread.

Treatment Plan

Your health care provider will determine a treatment plan for you based on the location and spread of any tumors.

Drug Therapies

Chemotherapy and radiation therapy shrink the tumor, especially if it is located in the rectum. Biological therapy, or immunotherapy, repairs, stimulates, or enhances the immune system's natural anticancer function.

Surgical and Other Procedures

Generally, the surgeon removes the tumor along with part of the colon or rectum and nearby lymph nodes, and reconnects the healthy portions of the colon or rectum.

Complementary and Alternative Therapies

A comprehensive treatment plan for colorectal cancer may include a range of complementary and alternative therapies.

Nutrition

Nutritional therapy can help slow the progression of disease, prevent its recurrence, and minimize the side effects of chemotherapy. Recommended foods include the following.

bulletCruciferous vegetables, such as broccoli, cabbage, brussel sprouts, cauliflower, and onions
bulletA high-fiber (whole grains and legumes), low-protein diet
bulletFats from vegetable and fish sources, including nuts, seeds, cold-water fish

Potentially beneficial nutrient supplements include the following.

bulletBromelain (500 mg twice daily between meals), taken with turmeric (Curcuma longa), 250 to 500 mg a day
bulletOmega-3 and omega-6 oils (fish oil, evening primrose oil), 3 to 6 g a day
bulletLactobacillus acidophilus (1 capsule with meals)
bulletFor patients receiving chemotherapy, coenzyme Q10 (200 mg a day)

In addition, the following supplements can make up for deficient nutrients.

bulletFolic acid (800 mg to 1,200 mcg a day), taken with vitamin B12 (1,200 mcg a day)
bulletCalcium (1,000 mg a day)
bulletVitamin E (800 IU a day)
bulletSelenium (200 to 400 mcg a day)
bulletBeta-carotene (50,000 IU a day)
bulletVitamin C (3 to 6 g a day)

Herbs

Formulas containing tumor-suppressing, immune-stimulating, and antimutagenic constituents (to counter changes in the DNA of cells) are traditionally used for treating cancer. These include the following.

bulletLicorice root (Glycyrrhiza glabra)
bulletRed clover (Trifolium pratense)
bulletBurdock (Actium lappa)
bulletQueen of the meadow (Stillingia sylvatica)
bulletBarberry (Berberis vulgaris)
bulletPoke root (Phytolacca americana)
bulletPrickly ash bark (Xanthoxylum americanum)
bulletBuckthorn bark (Rhamnus purshiana) with potassium iodide salts. This is best taken as a tea (2 to 3 cups a day) or tincture (30 to 60 drops twice daily).

These herbs are generally available as dried extracts (pills, capsules, or tablets), teas, or tinctures (alcohol extraction, unless otherwise noted). Dose for teas is 1 heaping tsp./cup water steeped for 10 minutes (roots need 20 minutes).

Homeopathy

An experienced homeopath could prescribe a regimen for treating colorectal cancer that is designed especially for you. Some of the most common acute remedies, particularly for treating the side effects of chemotherapy, are listed below.

bulletArsenicum for anxiety and nausea with restlessness and burning pains
bulletIpecac for nausea unrelieved by vomiting
bulletNux vomica for cramping, sharp abdominal pains with anger and collapse

Acute dose is three to five pellets of 12X to 30C every one to four hours until symptoms are relieved.

Prognosis/Possible Complications

Metastasis, or spreading of the cancer to other organs, such as the liver and lungs, is a serious concern. A temporary or permanent colostomy, in which part of the colon is brought through the abdomen and opened in order to empty waste from the body, may be needed.

Following Up

After surgery, your provider may perform further tests to make sure the cancer has not returned or spread. Pregnancy can complicate both the detection and treatment of colorectal cancer. Discuss your concerns with your health care provider.

Supporting Research

Blumenthal M, ed. The Complete German Commission E Monographs. Boston, Mass: Integrative Medicine Communications; 1998:467.

Boik J. Cancer and Natural Medicine. Princeton, Minn: Oregon Medical Press; 1995:125, 147.

Cecil R, ed. Cecil Textbook of Medicine. 20th ed. Philadelphia, Pa: W.B. Saunders; 1996.

Cappell MS. Pregnancy and Gastrointestinal Disorders. Gastroenterol Clin North Am. 1998;27(1).

Dambro MR. Griffith's 5-Minute Clinical Consult. 1999 ed. Baltimore, Md: Lippincott Williams & Wilkins, Inc.; 1999.

Devita VT, ed. Cancer: Principles and Practice of Oncology. 5th ed. Philadelphia, Pa: Lippincott-Raven Publishers; 1997.

Fauci AS, Braunwald E, Isselbacher KJ, et al, eds. Harrison's Principles of Internal Medicine. 14th ed. New York, NY: McGraw-Hill; 1998.

Krishnan K, Ruffin MT, Brenner DE: Clinic models of chemoprevention for colon cancer. Hematol Oncol Clin North Am. 1998;12(5).

Morrison R. Desktop Guide to Keynotes and Confirmatory Symptoms. Albany, Calif:Hahnemann Clinic Publishing; 1993:40,42,192,274.

Nijhoff WA, Grubben MJ, Nagengast FM, et al. Effects of consumption of brussel sprouts on intestinal and lymphocytic glutathione s-transferases in humans. Carcinogenesis. 1995;9:2125-2128.

Pawlowicz Z, Zachara BA, Trafikowska U, et al. Blood selenium concentrations and glutathione peroxidase activities in patients with breast cancer and with advanced gastrointestinal cancer. J Trace Elem Electrolytes Health Dis. 1991;4:275-277.

Werbach M. Nutritional Influences on Illness. New Canaan, Conn: Keats Publishing Inc; 1987:110,116.

Yamada T, ed. Textbook of Gastroenterology. 2nd ed. Philadelphia, Pa: Lippincott-Raven Publishers; 1995.

Copyright © 2000 Integrative Medicine Communications

The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. No claims or endorsements are made for any drugs or compounds currently marketed or in investigative use. This material is not intended as a guide to self-medication. The reader is advised to discuss the information provided here with a doctor, pharmacist, nurse, or other authorized healthcare practitioner and to check product information (including package inserts) regarding dosage, precautions, warnings, interactions, and contraindications before administering any drug, herb, or supplement discussed herein.